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HiTrap Capto Core 700, 5 x 1 ml

HiTrap Capto Core 700, 5 x 1 ml
HiTrap Capto Core 700 is a ready-to-use 1 ml column, prepacked with Capto Core 700, for intermediate purification and polishing of viruses and other large biomolecules in flow-through mode, Each bead has a ligand-activated core and an outer layer without ligands, The layer prevents the large targets from entering into the beads whereas proteins and other impurities enter into the core where they bind to the hydrophobic and positively charged octylamine ligands, HiTrap columns are easy used manually together with a syringe, with a lab pump or a chromatogtaphy system such as ÄKTA design, HiTrap Capto Core 700 HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess medium for intermediate purification and polishing of viruses and other large biomolecules. High capacity and productivity in flowthrough mode. Wide operational window of pH and conductivity. Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification. Capto Core 700 is a novel, layered bead chromatography medium consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (M_r 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

Package Content: 5 PCE

Reference Num.: GE17548151