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Capto L, 5 mL

Capto L, 5 mL
Capto L is an affinity chromatography medium for purification of antibodies and antibody fragments, The ligand, recombinant protein L ligand, has strong affinity to the variable region of antibody’s kappa light chain, Capto L is therefore particular suitable for purification of a wide range of different-sized antibody fragments such as Fabs, single-chain variable fragments (scFv) and domain antibodies (dAbs), Capto L, 5 ml Capto L is a BioProcess chromatography medium (resin) for the capture of antibodies and antibody fragments. It combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein, L ligand, which has a strong affinity to the variable region of antibody kappa light chains. Capto L is suitable for the capture of a wide range of antibody fragments such as Fabs, single-chain variable fragments (scFv), and domain antibodies (Dabs). High binding capacity, low ligand leakage, and selectivity for a broad range of antibody fragments reduces process time and amount of medium. Enables a platform approach for purification of antibody fragments. Increased productivity, process economy, and process design flexibility due to rigid matrix. The high binding capacity and selectivity for a broad range of antibody fragments makes Capto L an excellent capture platform for antibody fragments containing kappa light chains. Using Capto L requires minimal optimization and it produces high purity in one separation step. This results in significant savings in costs, effort, and time during process development. In addition, Capto L provides several advantages in manufacturing processes because the high selectivity of affinity capture reduces the number of subsequent polishing steps. Capto L is available in prefilled PreDictor 96-well plates, PreDictor RoboColumn™, as well as HiTrap and HiScreen prepacked columns for efficient high-throughput process development or small-scale purification

Package Content: 1 PCE

Reference Num.: GE17547806