La imagen es solo una referencia, puede diferir e incluir accesorios no disponibles en el producto.

 

Capto MMC ImpRes, 25 ml

Capto MMC ImpRes, 25 ml
Capto adhere ImpRes is a multimodal cation exchange medium with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges. The column is an excellent choice for method optimization and parameter screening. The multimodal functionality gives a different selectivity compared with traditional ion exchange columns and it binds proteins at high or low ionic strength in combination with high resolution- and yield. Capto MMC ImpRes, 25 ml Capto MMC ImpRes is a weak cation exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules. High yields achieved through the high-resolution beads and selectivity of the ligand. Efficient removal of aggregates, viruses, and main contaminants in MAb processes. Enables use of a platform approach to MAb process development. Displays a broad pH/salt operational window. Suitable for polishing of antibody fragments. The weak cation exchange multimodal ligand enables high selectivity in a broad pH/salt window compared with traditional ion exchangers, which allows the use of Capto MMC ImpRes in a variety of process conditions to solve challenging purification problems. The multimodal cation exchanger ligand of Capto MMC ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions. Capto MMC ImpRes Simplifies Optimization Capto MMC ImpRes can be used for initial or final polishing steps in MAb purification processes, as well as for polishing of antibody fragments such as domain antibodies (DAbs).The wide window of operation for conductivity and/or pH simplifies the process as conditioning after the protein A step can be omitted. When working with sensitive MAbs, the wide window of operation simplifies optimization of conditions. Capto MMC ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development. As member of the BioProcess media range, Capto MMC ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.

Package Content: 25 MLT

Reference Num.: GE17371601