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Capto adhere ImpRes, 100 ml

Capto adhere ImpRes, 100 ml
Capto adhere ImpRes is a multimodal anion exchange medium for intermediate purification and polishing of monoclonal antibodies after the Protein A capture step, giving the possibility to design a two step chromatographic downstream process The multimodal functionality gives a different selectivity compared with traditional ion exchange columns and it binds proteins at high or low ionic strength in combination with high resolution- and yield. Capto adhere ImpRes, 100 ml Capto adhere ImpRes is a strong anion exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules. High yields achieved through the high-resolution beads and selectivity of the ligand. Efficient removal of aggregates, viruses, and main contaminants in MAb processes. Enables use of a platform approach to MAb process development. Allows separation of MAb charged variants. Capto adhere ImpRes is designed to allow effective MAb polishing in the second or third step of a purification scheme downstream of the protein A capture step. Polishing can be performed in either bind and elute (binding) or flowthrough (nonbinding) modes. The multimodal anion exchanger ligand of Capto adhere ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions. Capto adhere ImpRes Helps Solve Your Purification Problems The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed. Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development. As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.

Package Content: 100 MLT

Reference Num.: GE17371502