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HITRAP CAPTO MMC, 5X1ML

HITRAP CAPTO MMC, 5X1ML
HITRAP CAPTO MMC, 5X1ML, 5 EA, High dynamic binding capacity at high conductivity, High volume throughput, New selectivity allows binding in the presence of, Category: Protein Purification, Chromatography Columns and Media, Ion Exchange, HiTrap Capto MMC HiTrap Capto MMC is prepacked with Capto MMC, a multimodal BioProcess ion exchange medium. The multimodal functionality gives a different selectivity compared with traditional ion exchangers and it binds proteins at high or low ionic strength. High dynamic binding capacity at high conductivity. Selectivity allows binding in the presence of salt. High volume throughput. HiTrap Capto MMC can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges. The multimodal functionality gives a different selectivity compared with traditional ion exchangers including binding of proteins regardless of ionic strength of the loading material . This means that the medium may be used for direct load of clarified feedstocks, without prior dilution to reduce the conductivity of the starting material. To reduce tedious sample preparation, the top filter in HiTrap Capto MMC has been optimized for loading sonicated unclarified cell lysate directly on the column. The Capto MMC ligand may interact with proteins in many different ways. It contains a carboxyl group, and thus it is a weak cation exchanger. However, in addition to the ionic interactions several other types of interactions are involved, including hydrogen bonding and hydrophobic interaction.

Package Content: 1 PCE

Reference Num.: GE11003273