Cot I Human DNA

Cot I Human DNA
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Número de artículo.: BN401001 Solicitar Precio para 1 Paquete
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Cot I Human DNA

Enzymes, DNA and Fine Chemicals

COT I Human DNA is prepared exclusively from male human placental DNA by shearing, denaturing, and reannealing under conditions that enrich repetitive elements, so the COT I fraction of human genomic DNA consists largely of rapidly annealing repetitive elements.
COT I Human DNA can be used for suppressing crosshybridization to human repetitive DNA in filter and microarray hybridizations and in situ hybridization experiments.
Repetitive elements present in a probe may result in unspecific hybridization signals.
To enable specific hybridization of the probe to the chromosomal target site the probe is denatured together with an excess of unlabeled COT I Human DNA as a competitor.
As a result single-copy gene hybridization is not hindered by repetitive sequences.

Cat. Number : BN401001

Package Content : 500 µg
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Descripción de tipo de producto: Enzymes